Effects when Combining IFN - Uncoupled Anti - HIV and Immune - Enhancing
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Interferon-alpha, immune activation and immune dysfunction in treated HIV infection
Type I interferons (IFNs) exert anti-viral effects through the induction of numerous IFN-stimulated genes and an immunomodulatory effect on innate and adaptive immune responses. This is beneficial in controlling virus infections but prolonged IFN-α activity in persistent virus infections, such as HIV infection, may contribute to immune activation and have a detrimental effect on the function of...
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تاریخ انتشار 2005